"DNA sensors in metabolic and cardiovascular diseases: Molecular mechanisms and therapeutic prospects"

Hyosang Kwak#, Ein Lee#, Rajendra Karki, Immunological reviews, 2024 Aug,

"Implications of inflammatory cell death-PANoptosis in health and disease"

Hyun Bae#, Yeonseo Jang#, Rajendra Karki* & Joo-Hui Han*, Archives of Pharmacal Research, 2024 Jul, 47(7), 617-631

"A comparative study of apoptosis, pyroptosis, necroptosis, and PANoptosis components in mouse and human cells"

Sk Mohiuddin Choudhury, Roman Sarkar, Rajendra Karki, Thirumala-Devi Kanneganti, Public Library of Science one, 2024 Feb, 19(2), e0299577

"Inhibition of the RPS6KA1/FoxO1 signaling axis by hydroxycitric acid attenuates HFD-induced obesity through MCE suppression"

Hyung-Won Lee, Rajendra Karki , Joo-Hui Han, Phytomedicine : international journal of phytotherapy and phytopharmacology, 2024, 128, 155551

"NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress"

Joo-Hui Han #, Rajendra Karki #, R K Subbarao Malireddi, Raghvendra Mall , Roman Sarkar, Bhesh Raj Sharma , Jonathon Klein, Harmut Berns , Harshan Pisharath, Shondra M Pruett-Miller, Sung-Jin Bae , Thirumala-Devi Kanneganti, Nature Communications, 2024, 15(1), 1739

"Immune regulator IRF1 contributes to ZBP1-, AIM2-, RIPK1-, and NLRP12-PANoptosome activation and inflammatory cell death (PANoptosis)"

Sharma B.R.; Karki R.; Rajesh Y.; Kanneganti T.-D., The Journal of biological chemistry, 2023 Sep, 299(9), 105141

"NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs"

Sundaram B.; Pandian N.; Mall R.; Wang Y.; Sarkar R.; Kim H.J.; Malireddi R.K.S.; Karki R.; Janke L.J.; Vogel P.; Kanneganti T.-D., Cell, Jun 22, 186(13), 2783-2801

"PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis"

Karki R.; Kanneganti T.-D., Current Opinion in Immunology, 2023 Aug, 83, 102348

"ADAR1 and ZBP1 in innate immunity, cell death, and disease"

Karki R.; Kanneganti T.-D., Trends in Immunology, 2023 Mar, 44(3), 201-216

"Regulated cell death pathways and their roles in homeostasis, infection, inflammation, and tumorigenesis"

Lee, Ein#; Song, Chang-Hyun#; Bae, Sung-Jin; Ha, Ki-Tae; Karki, Rajendra∗, Experimental and Molecular Medicine, 2023 Aug, 55(8), 1632-1643

"Pancancer transcriptomic profiling identifies key PANoptosis markers as therapeutic targets for oncology"

Mall R.; Bynigeri R.R.; Karki R.; Malireddi R.K.S.; Sharma B.R.; Kanneganti T.-D., Nucleic Acids Research Cancer, 2022, 4(4), zcac033

"Innate immunity, cytokine storm, and inflammatory cell death in COVID-19"

Karki R.; Kanneganti T.-D., Journal of translational medicine, 2022, 20(1), 542

"Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation"

Wang Y.; Karki R.; Mall R.; Sharma B.R.; Kalathur R.C.; Lee S.; Kancharana B.; So M.; Combs K.L.; Kanneganti T.-D., Cell reports, 2012 Oct, 4;41(1), 111434

"Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method"

Wang Y.; Pandian N.; Han J.-H.; Sundaram B.; Lee S.J.; Karki R.; Guy C.S.; Kanneganti T.-D., Cellular and Molecular Life Sciences, 2022 Sep 28, 79(10), 531

"ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection"

Karki R.#; Lee S.#; Mall R.; Pandian N.; Wang Y.; Sharma B.R.; Malireddi R.K.S.; Yang D.; Trifkovic S.; Steele J.A.; Connelly J.P.; Vishwanath G.; Sasikala M.; Reddy D.N.; Vogel P.; Pruett-Miller S.M.; Webby R.; Jonsson C.B.; Kanneganti T.-D., Science Immunology, 2022 Aug, 26;7(74), eabo6294